SIRT5 and cancer: To evaluate the roles of four well-known succinylation regulators (CPT1A, KAT2A, SIRT5, and SIRT7), we utilized the TCGA pan-cancer dataset to analyze the expression patterns and prognostic prediction values in 10 relatively common tumors including ESCA, STAD, LUSC, LUAD, LIHC, KIRP, KIRC, COAD, BRCA, and BLCA.