Next, we were interested in the role of circPostn in MI-related cardiac remodeling in vivo. Given that previous studies have identified that collagen, α-SMA, ANP, and BMP serve as the markers of myocardial fibrosis and remodeling (Wang J. et al., 2020; Zhang B. F. et al., 2020), we further evaluated the effect of circPostn on these factors. The gene discussed is ACTA1; the disease is Myocardial fibrosis.