AKT1 and gastric cancer: Here, bioinformatic analysis revealed that circHIPK3 possessed responsive elements of numerous miRNAs, including miR-637 and DIANA-TarBase v8.0 software revealed that AKT1 was a potential target of miR-637, thus we hypothesized that circHIPK3 played a role in the tumorigenesis and development of GC by regulating miR-637/AKT1 axis.