SQSTM1 and non-small cell lung carcinoma: confirmed that staurosporine added to NSCLC cells activates autophagy as measured by increase in LC3-II/LC3-I ratio, reduced mTOR activity as shown by dephosphorylated/less phosphorylated ribosomal protein S6 (RP-S6), degradation of p62 and downregulation of Flightless I, controlling the binding activity of p62 to LC3 (80).