Accelerates cell proliferation and cell migration (97).DNMT1 causes miR34a promoter methylation and suppression, leading to FOXM1 upregulation and promotes LC stemness (98).Regulates cell differentiation, and metastasis viaCCAT2/miR-34a/FOXM1.FOXM1 activates CCAT2 transcription (99). The gene discussed is CCAT2; the disease is laryngotracheoesophageal cleft.