BAK1 and hepatocellular carcinoma: Circ-0051443, a circRNA that is transported from normal cells to HCC cells via exosomes, suppresses HCC progression by sponging miR-331-3p to induce the expression of BAK1 (61). CircARSP91, a circRNA that is suppressed by AR in an ADAR1-dependent manner, functions as a tumor suppressor in HCC (62).