Thus, we propose that the influence of SSA/DA treatment at the transcriptome level was directed toward suppression of tumor promoting genes (GRHL2, MUC16, MACC1), and the protective effects of the upregulated DEGs were small or indirect (MPPED1, TMEM132C, SEPTIN14); however, further studies are needed to confirm this hypothesis. This evidence concerns the gene SEPTIN14 and neoplasm.