MACC1 and colonic neoplasm: The three most upregulated genes in the treated group were metallophosphoesterase domain containing 1 (MPPED1), transmembrane protein 132C (TMEM132C), and septin 14 (SEPTIN14); in contrast, the three most downregulated genes in the SSA/DA and SSA therapy groups were grainyhead like transcription factor 2 (GRHL2), mucin 16 (MUC16), and MET transcriptional regulator (MACC1—Metastasis-Associated in Colon Cancer) (Table 2, Figure 2).