MC1R and colorectal carcinoma: In the present study the 13 IRGs that were strongly associated with CRC prognosis—CXCL1, F2RL1, LTB4R, GPR44, ANGPTL5, BMP5, RETNLB, MC1R, PPARGC1A, PRKDC, CEBPB, SYP, and GAB1—were used in the classifier investigation.