For example, AGR3 has been shown to facilitate the stemness of colorectal cancer by regulating Wnt/β-catenin signaling (35); STC2 has been shown to be involved in resistance to treatment with EGFR tyrosine kinase inhibitors and to promote the progression of lung cancer by regulating JUN/AXL signaling (36). Here, AGR3 is linked to lung carcinoma.