VDAC1 and breast cancer: The main objectives of this article were as follows: (i) evaluate the association of VDAC1 expression with Cytc in BC; (ii) investigate the correlation of various clinical features and 5-year disease-free survival (5-DFS) of BC with VDAC1 and Cytc, respectively, and (iii) explore the effects of VDAC1 on cell proliferation and migration in BC cell line.