LGALS3 and hydrops fetalis: A high GAL3 level was associated with HF severity, such as a high New York Heart Association HF class; high systolic blood pressure; high creatinine, N-terminal prohormone of brain natriuretic peptide, IL-6, and C-reactive protein levels; and lower maximal oxygen consumption [152, 153], as well as increased left ventricular weight and echocardiographic changes in the left ventricular end-diastolic volume [154, 155].