GOLPH3 and colorectal carcinoma: In CRC patients, the difference in serum GOLPH3 concentration at 1 week after (median 7.31 ng/mL) and before (median 7.38 ng/mL) surgery was also significant (P < 0.01), as was the difference between before or 1 week after surgery and one month after surgery (median 5.43 ng/mL) (P < 0.001) (Figure 5(b)).