Notably, some genes in the turquoise module, including “BTG3,” “C12orf41,” “CCR2,” “COPB2,” “DYNLL2,” “ETNK1,” “GIMAP4,” “GIMAP8,” “HSPA1A,” “LFNG,” “LOC653171,” “LOC731878,” “RAB10,” “TMEM60,” “TNFAIP3,” and “TNFAIP8L2,” had high gene significance for SSc-PAH (Figures 2(e) and 2(f)). This evidence concerns the gene COPB2 and systemic sclerosis.