In dataset GSE33463, the expression of four genes, B cell translocation gene 3 (BTG3), C-C motif chemokine receptor 2 (CCR2), member RAS oncogene family (RAB10), and transmembrane protein 60 (TMEM60), was notably increased or decreased in the PBMCs of SSc-PAH patients compared with the controls (Figures 3(a)–3(d)). Here, TMEM60 is linked to pulmonary arterial hypertension.