CRP and appendicitis: Mostly appendicitis is diagnosed on clinical examination but can be challenging in females and children.1 Total leukocyte count is not always a good diagnostic criteria in acute appendicitis but when combined with clinical examination, it is helpful for appendectomy.2 C-reactive protein and bilirubin are raised significantly in acute appendicitis (96.6%).3 Sensitivity of TLC is more than (90%) in the diagnosis of acute appendicitis.4 Raised bilirubin level strongly supports and depicts appendicular perforation.