Cytotoxic T lymphocytes and a variety of cytokines, including the CXC family included CXCR3 and CXCR6, as well as the chemokines CXCL9, CXCL10, CXCL11, and CXCL16(the only known natural ligand of CXCR6), play an important role in the pathogenesis of vitiligo (van den Boorn et al., 2009; Rashighi et al., 2014; Li et al., 2017; Aguilera-Durán and Romo-Mancillas, 2020). Here, CXCR6 is linked to vitiligo.