Furthermore, the results for nine lncRNAs (lncRNA-LINC00173, lncRNA-H19, lncRNA-HDAC6, lncRNA-POP4, lncRNA-PTEN, lncRNAAKT3, lncRNA-DICER1, lncRNA-NF1, and lncRNA-MUM1) with significant changes were verified by RT-qPCR, and all these lncRNAs were much more highly expressed in PCOS follicular fluid exosome samples than in non-PCOS follicular fluid exosome samples. The gene discussed is POP4; the disease is polycystic ovary syndrome.