The analysis demonstrated that the protein levels of TBK1 expression were significantly correlated with poorer OS (CPTAC: HR=2.23, P = 0.007; Our cohort: HR=2.92, P=0.002) and RFS (CPTAC: HR=1.73, P=0.019; Our cohort: HR=1.72, P=0.039) in patients with HCC (Figures 2C, D). The gene discussed is TBK1; the disease is hepatocellular carcinoma.