Moreover, patients with a more advanced T classification (P = 0.020), severer vascular invasion (P = 0.031), higher degree of liver fibrosis (P = 0.017), and higher value of platelet-to-albumin ratio (P = 0.027) tended to have higher mRNA expression levels of TBK1 (Figures 3A, B). Here, TBK1 is linked to Hepatic fibrosis.