Previous studies also demonstrated aberrant TBK1 expression and its pro-tumor effects in multiple cancers, including the promotion of migration and invasion in melanoma (11), AXL-induced epithelial–mesenchymal transition in pancreatic cancer (12), and tamoxifen resistance by increasing the transcriptional activity of estrogen receptor α in breast cancer (13). This evidence concerns the gene TBK1 and pancreatic neoplasm.