Figure 2B shows the ESTIMATE and ssGSEA scores of the 29 immune-related gene sets in the two clusters. Compared with the immune-activated cluster, the patients in the immunosuppressive cluster presented relatively lower immune score, lower stromal score, higher tumor purity, and lower levels of immune-related gene sets. Patients in the immunosuppressive cluster also exhibited significantly lower expression levels of T cell inhibitors (Figure 2C), major histocompatibility complexes (Figure 2D), and T cell stimulators (except for TNF superfamily member 14; Figure 2E). The gene discussed is TNF; the disease is neoplasm.