The subgroup analysis of patients with chronic PA colonization (n = 15) has found that CF individuals with MBL insufficiency have both a shorter interval between first PA infection and onset of PAC (0.01 vs. 4.6 years, p < 0.04) as well as a lower median age at transition to chronic PA colonization (9.8 vs. 16.4 years, p < 0.03) compared to MBL sufficient patients (Figure 1). Here, MBL2 is linked to infection.