Regarding post-GC MBC, CVID patients displayed a significant reduction (vs. HD) of CD21+ CD24+ IgMD+ MBC (16 vs 31 cells/μl, p=0.0006), associated with normal or slightly increased (p>0.05) CD21-CD24- and CD21- CD24++ IgMD+ MBC numbers (Supplementary Figure 2). Here, CD24 is linked to common variable immunodeficiency.