AKT1 and hepatocellular carcinoma: The results showed that BiHT induced almost complete inhibition of phosphorylation of AKT and ERK1/2 in BT-474, SKOV-3, and NCI-N87, while it slightly suppressed phosphorylation of AKT and ERK in HCC-1954 and ERK in MCF-7, but failed to inhibit AKT/ERK signaling pathways in JIMT-1 cell line.