FMO5 and aspergillosis: NADPH oxidase-deficient mice are extremely susceptible to pulmonary aspergillosis; however, the role of NADPH oxidase in aspergillosis is complex and must involve oxidative killing of A. fumigatus, as well as the control of lung inflammation, and probably does not reflect merely the absence of NETosis (Morgenstern et al., 1997; Winterbourn et al., 2016).