EZH2 exhibits gene amplification and higher levels of expression in many human malignancies, such as gastric cancer, colon cancer, breast cancer, lymphoid hematopoietic tumors, liver cancer, and nephroblastoma (Su et al., 2003; Mimori et al., 2005; Raman et al., 2005; Sudo et al., 2005; Matsukawa et al., 2006; Saramaki et al., 2006; Shi et al., 2007), and is closely related to tumorigenesis and tumor progression. The gene discussed is EZH2; the disease is neoplasm.