The inability to promptly defeat a viral infection can elicit a cytokine storm, in which pro-inflammatory molecules including Interleukin-1β (IL-1β), Interleukin-6 (IL-6), and Tumor necrosis factor (TNF-α) are released in pathogenic concentrations causing systemic hyperinflammation (Iannaccone et al., 2020). This evidence concerns the gene TNF and viral infectious disease.