Wu et al. (2020) presented six black patients with COVID-19 and apo L1 (APOL1) variant who experienced worsening in renal function and proteinuria rapidly. The renal biopsies of all these patients showed collapsing glomerulopathy without the evidence of direct kidney infection, indicating that APOL1 variant was associated with high-risk of collapsing glomerulopathy in patients with COVID-19 (Wu et al., 2020; Shetty et al., 2021). This evidence concerns the gene APOL1 and COVID-19.