TJP1 and metabolic dysfunction-associated steatotic liver disease: In this study, GE significantly prevented metabolic endotoxemia and restored intestinal integrity by boosting the mRNA expression of two tight-junction proteins (ZO-1 and occludin) in HFD-fed mice, which indicated that the ability of GE to relieve NAFLD was attributed to the blunting of LPS leakage and repair of the intestinal barrier.