Among the Immune score, the basal subtype had the highest average Immune score, followed by the Her2+ subtype, LumA third, and LumB the lowest (p = 2.7e − 12); Similarly, in breast cancer subtypes, the order of Stromal score from high to low is LumA > Her2+ > LumB > Basal (p < 2.2e − 16). Here, TMEM43 is linked to breast carcinoma.