Examining the mutual exclusiveness suggests that events happened in GPR139 and GPR142 were responsible to occur again in pan-cancer (GPR139 exposed in BRCA, GBM, LGG, PCPG, and SARC) while GPR142 exposed in ESCA, LIHC, LUAD, LUSC, PAAD, STAD, TGCT, THCA, and UCS) as represented in Figure 3. Here, GPR139 is linked to cancer.