It provides Alzheimer's disease-linked gene changes of the amyloid protein precursor, α-secretase, β-secretase, presenilin 1, presenilin 2, and tau protein in experimental post-ischemic injury in the CA1 and CA3 areas of the hippocampus and medial temporal cortex. The gene discussed is MAPT; the disease is early-onset autosomal dominant Alzheimer disease.