HDAC1 and Huntington disease: To explore a more inclusive list of potentially therapeutically relevant genes, we examined all expression changes, regardless of their statistical significance, which revealed that of the 42 genes previously reported to be restored by HDACi 4b, 25 showed a change toward the wild type levels after RGFP109 administration in R6/1 mice in our study (Figure 2D and Supplementary Data Sheet S1), providing a list of genes whose expression levels are consistently ameliorated by specific HDAC1/3 inhibitors across different HD models.