Within the last 5 years, various other genes could be identified in the small percentage of patients without PKD1 or 2 mutations: mutations in GANAB cause generally mild cases of ADPKD and polycystic liver disease [46], patients with DNAJB11 variants have non-enlarged or atrophic kidneys with interstitial fibrosis [47] and mutations in ALG9 also cause polycystic kidney and/or liver disease [48], but the further characterization of disease progression in the latter two is still lacking. This evidence concerns the gene GANAB and autosomal dominant polycystic kidney disease.