To further evaluate the long-term neuroprotective effects of NLRP3 inhibitor MCC950 on NEC-induced cognitive impairments, Morris water maze test was performed in 28-day-old breastfed mice, age-matched mice that had NEC as newborns, and MCC950-treated NEC counterparts (Fig. 5a). This evidence concerns the gene NLRP3 and necrotizing enterocolitis.