IFNA1 and infection: Reactome pathway analysis on upregulated and downregulated genes in the lungs of SARS-CoV-2-infected rhesus macaques showed that genes significantly upregulated by infection, included pathway enrichment for genes involved in “Neutrophil degranulation”, “Innate Immune system”, “Immune system” and “IFN signaling” (Supplementary Table 1 and Supplementary Data 4A).