CXCR3 and COVID-19: Of the Hepatitis-induced pathway genes that are upregulated in juvenile COVID-19 diseased lungs, CXCL-10 (C-X-C Motif Chemokine Ligand 10) is a chemokine associated with severe disease in COVID-19 in humans47, but can also be involved in the recruitment of CXCR3 (C-X-C Motif Chemokine Receptor 3) expressing immune cells.