SERPIND1 and Insulin resistance: Significant correlations of coagulation proteins with insulin resistance, as determined by HOMA-IR, were also seen for antithrombin III (p < 0.0001), heparin cofactor 2 (p < 0.001), P-selectin (p < 0.0001), fibronectin (p < 0.01), vitamin K dependent protein S and alpha 2 antiplasmin (p < 0.05, respectively) (Table 2).