BMP2, ALDH1A2, TNC, SHC4, GSN, SIK1 were down-regulated at 7d of FD relative to controls, while LOC417800, HCK, WNT9A, KIAA1199, CLEC3B, SLCO1C1 and RHOB were upregulated in the FD eye compared to controls (Supplementary Table 1). The gene discussed is CEMIP; the disease is Fabry disease.