TRIM23 is upregulated in CRC, it binds p53, inducing its ubiquitination and promoting colorectal cell proliferation [149]; TRIM24 (transcription intermediary factor 1α-TIF1α), mRNA and protein levels were higher in CRC tissues compared to controls, indicating this TRIM is a potential negative prognostic marker. This evidence concerns the gene TRIM24 and colorectal carcinoma.