Increasing evidence shows that eEF2K is highly expressed in a variety of tumor tissues and that it is related to the development and prognosis of several kinds of malignancies such as breast cancer, ovarian cancer, colon cancer, glioma, medulloblastoma, hepatocellular carcinoma, and prostate cancer [7,8,9,10,11,12]. This evidence concerns the gene EEF2K and hepatocellular carcinoma.