EEF2K and neoplasm: It was initially speculated that this cytotoxic activity of 30 is related to its inhibitory effect on PKC, but it was later found that 30 induces tumor cell apoptosis through inhibition of eEF2K by using reverse phase-protein array (RPPA), cell viability (MTS) assay, and eEF2K knockdown technology [14,75,102].