Prior to or following CN diagnosis, a total of 26 patients (for 17 of whom, the germline DICER1 status was not documented) developed DICER1-related tumors (e.g., PPB, multinodular goiter, embryonal rhabdomyosarcoma, malignant teratoid ciliary body medulloepithelioma, and others). This evidence concerns the gene DICER1 and multinodular goiter.