FGF23 and Insulin resistance: Similar results were obtained by Hanks et al., who found an independent relationship between FGF23 and several indices of insulin resistance, which were much more apparent in subjects with normal kidney function as compared to patients with CKD stages 3–5; in the same study the authors confirmed a strong relationship between analyzed interleukins (IL6, IL10), C reactive protein and serum FGF23 [32].