By considering that the patients were non-diabetic and the blood glucose as well as the glycated Hb (HbA1C) content did not significantly differ between patients and control subjects, we can reasonably argue that CML adducts arise from lipid peroxidation, the occurrence of which in HF patients is well documented, as recently reviewed by Gianazza et al. [16]. Here, GSTM1 is linked to hydrops fetalis.