ALB and hydrops fetalis: Besides these issues that need to be clarified, we can focus on some key points confirmed by the present study, particularly (i) that HF subjects undergo significant oxidative stress/lipid peroxidation, (ii) that albumin is the main plasma target and the key detoxifier at the extracellular level of RCS, (iii) that GO is formed to a high degree in HF patients, and (iv) that CML is stable enough to be detected as a marker.