Concerning the lncRNAs that directly modulate HIF1 expression, in nasopharyngeal carcinoma HIF-1α mRNA stability is mediated by the lncRNA DANCR (differentiation antagonizing non-protein coding RNA); this is required for the interaction between HIF-1α mRNA and the complex NF90/NF45 which was found increase HIF-1α mRNA stability [141]. This evidence concerns the gene HIF1A and nasopharyngeal carcinoma.