NR3C2 and diabetic kidney disease: The benefit with respect to CKD progression was lower than that reported with Canagliflozin in the CREDENCE trial, more likely because SGLT2-i were allowed in the FIDELIO-DKD, thus leading to a higher renoprotection in the placebo group, whereas patients treated with mineralocorticoid receptor antagonists were excluded from the CREDENCE trial [78].