Some FGFR aberrations commonly found in GBM are FGFR1 (and FGFR3) translocations that create fusion genes with transforming acidic coiled-coil genes (FGFR-TACC), leading to constitutive receptor activation and aberrant nuclear localization/aneuploidy [137]. Here, FGFR3 is linked to glioblastoma.