Other examples include enhanced chemotaxis and proliferation of human U87 GBM cells resulting from EGFR signaling mediated by formylpeptide receptor (FPR) activation [231], and increased migration due to GPCR CXC chemokine receptor 4 (CXCR4) activation of PDGFRβ in human GL15 GBM cells [232]. The gene discussed is PDGFRB; the disease is glioblastoma.