PDGFRB and glioblastoma: In the TCGA-GBM dataset, PDGFRA is highly amplified (40%) and mutated (20%) in the PN subtype, whereas PDGFRB is mutated to a small extent in the CL (2.6%) and PN (4.0%) subtypes, with copy number loss (57.1%) prominent in the G-CIMP subset.