Recent studies have shown that the administration of the 5-HT2B/5-HT2C agonist in the dorsal hippocampus (DH) of rats induced anxiety, but the administration of selective 5-HT2C agonists, MK-212 and RO-600175, promoted an anxiolytic effect, indicating that local activation of 5-HT2C causes the opposite effect of local activation of 5-HT2B. Here, HTR2B is linked to Anxiety.