EZH2 and pachyonychia congenita: Exposure of F-box and WD repeat domain-containing 7 (FBW7) to EZH2 causes the degradation of EXH2 in PC cells and inhibits tumour migration and invasion, indicating its role as a ligase of EZH2 that regulates EZH2 protein levels in PC and furthermore, its potential as a treatment strategy [85].