In particular, the reduced expression of members of the Wnt, Chemokine, and TGFβ signaling pathway are possibly critical for this effect, given that those pathways control many aspects of cell homeostasis [72,73], and have been proposed to contribute to cancer development [74,75,76] including AML [77,78,79]. This evidence concerns the gene TGFB1 and acute myeloid leukemia.