MYC and neoplasm: DAPT treatment in combination with radiation [48], gleevec and amph1D peptide [49], D341Med with HBMEC [50], and imatinib [51], resulted in an increase of apoptosis and radio-sensitivity in ihBTC2 cells [48]; the induction of neurosphere dispersion that resulted in cell death [49]; the downregulation of Bmi-1, CDK6, c-Myc, and CCND1 expression in D341Med, and a reduction in the tumor size and volume [50]; and the effective growth inhibition of GBM cells [51].