Representative images of IHC staining in HCC and LC tissue samples are shown in Figure 7C. However, in HCC, HIF-1α only correlated with VEGFR-2 at the mRNA expression level, and only with VEGF-A at the protein level (r = 0.563 p = 0.023, r = 0.509 p = 0.013, respectively; Pearson correlation test). This evidence concerns the gene HIF1A and laryngotracheoesophageal cleft.