Some examples of these are the integration of Hepatitis B virus into telomeres, as well as genes coding for proteins X and S, which induce inflammation and neoplasia; or Human Papilomavirus integration in oncogenes E6 and E7 in the cell genome, which suppress the p53 anti-tumor gene and promote cell proliferation while simultaneously alters cell-to-cell adhesion [7,8,9]. Here, TP53 is linked to neoplasm.