CD123 is a marker of blastic plasmacytoid dendritic cell neoplasm (BPDCN), but it is also overexpressed in other cancers, including AML, MDS, systemic mastocytosis, acute lymphoblastic leukemia, Hodgkin lymphoma and hairy cell leukemia [178,179,180]. This evidence concerns the gene IL3RA and acute myeloid leukemia.